4PY6

Crystal Structure of bromodomain of PFA0510w from Plasmodium Falciparum

Summary for 4PY6

• Entry DOI: 10.2210/pdb4py6/pdb
• Descriptor: Bromodomain protein, putative, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, bromodomain, malaria, protein binding
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 4
• Total formula weight: 72096.21

Authors

Fonseca, M.,Tallant, C.,Hutchinson, A.,Savitsky, P.,Krojer, T.,Filippakopoulos, P.,Loppnau, P.,Brennan, P.E.,von Delft, F.,Dong, A.,Josling, G.A.,Duffy, M.F.,Arrowsmith, C.H.,Bountra, C.,Hui, R.,Knapp, S.,Wernimont, A.K.,Structural Genomics Consortium (SGC) (deposition date: 2014-03-26, release date: 2014-04-30, Last modification date: 2024-02-28)

• Primary citation: Fonseca, M.,Tallant, C.,Hutchinson, A.,Savitsky, P.,Krojer, T.,Filippakopoulos, P.,Loppnau, P.,Brennan, P.E.,von Delft, F.,Dong, A.,Josling, G.A.,Duffy, M.F.,Arrowsmith, C.H.,Bountra, C.,Hui, R.,Knapp, S.,Wernimont, A.K.,Structural Genomics Consortium (SGC); Crystal Structure of bromodomain of PFA0510w from Plasmodium Falciparum; To be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)