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4PXQ

Crystal structure of D-glucuronyl C5-epimerase in complex with heparin hexasaccharide

Summary for 4PXQ
Entry DOI10.2210/pdb4pxq/pdb
Related4PW2
DescriptorD-glucuronyl C5 epimerase B, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (3 entities in total)
Functional Keywordsepimerization enzyme, multiple domain structure, heparan sulfate c5-epimerase, heparin, heparan sulfate, isomerase
Biological sourceDanio rerio (leopard danio,zebra danio,zebra fish)
Total number of polymer chains2
Total formula weight135737.20
Authors
Ke, J.,Qin, Y.,Gu, X.,Tan, J.,Brunzelle, J.S.,Xu, H.E.,Ding, K. (deposition date: 2014-03-24, release date: 2015-01-14, Last modification date: 2024-02-28)
Primary citationQin, Y.,Ke, J.,Gu, X.,Fang, J.,Wang, W.,Cong, Q.,Li, J.,Tan, J.,Brunzelle, J.S.,Zhang, C.,Jiang, Y.,Melcher, K.,Li, J.P.,Xu, H.E.,Ding, K.
Structural and Functional Study of d-Glucuronyl C5-epimerase.
J.Biol.Chem., 290:4620-4630, 2015
Cited by
PubMed: 25568314
DOI: 10.1074/jbc.M114.602201
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

數據於2024-03-27公開中

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