4PXQ
Crystal structure of D-glucuronyl C5-epimerase in complex with heparin hexasaccharide
Summary for 4PXQ
Entry DOI | 10.2210/pdb4pxq/pdb |
Related | 4PW2 |
Descriptor | D-glucuronyl C5 epimerase B, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | epimerization enzyme, multiple domain structure, heparan sulfate c5-epimerase, heparin, heparan sulfate, isomerase |
Biological source | Danio rerio (leopard danio,zebra danio,zebra fish) |
Total number of polymer chains | 2 |
Total formula weight | 135737.20 |
Authors | |
Primary citation | Qin, Y.,Ke, J.,Gu, X.,Fang, J.,Wang, W.,Cong, Q.,Li, J.,Tan, J.,Brunzelle, J.S.,Zhang, C.,Jiang, Y.,Melcher, K.,Li, J.P.,Xu, H.E.,Ding, K. Structural and Functional Study of d-Glucuronyl C5-epimerase. J.Biol.Chem., 290:4620-4630, 2015 Cited by PubMed: 25568314DOI: 10.1074/jbc.M114.602201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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