4PWQ
HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN of THE AMYLOID PRECURSOR PROTEIN
Summary for 4PWQ
Entry DOI | 10.2210/pdb4pwq/pdb |
Descriptor | Amyloid beta A4 protein (2 entities in total) |
Functional Keywords | heparin binding, dimerization, heparin binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 2 |
Total formula weight | 43524.16 |
Authors | |
Primary citation | Hoefgen, S.,Dahms, S.O.,Oertwig, K.,Than, M.E. The Amyloid Precursor Protein Shows a pH-Dependent Conformational Switch in Its E1 Domain. J.Mol.Biol., 427:433-442, 2015 Cited by PubMed: 25528641DOI: 10.1016/j.jmb.2014.12.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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