Summary for 4PVU
| Descriptor | Peroxisome proliferator-activated receptor gamma, (2R)-(4-chlorophenyl)[3-(trifluoromethyl)phenoxy]ethanoic acid (3 entities in total) |
|---|---|
| Functional Keywords | alpha-helices, small four-stranded beta-sheet, activator, tdna-binding, nucleus, obesity, receptor, transcription, transcription regulation |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus P37231 |
| Total number of polymer chains | 2 |
| Total molecular weight | 65718.33 |
| Authors | Pochetti, G.,Montanari, R.,Capelli, D.,Loiodice, F.,Laghezza, A.,Piemontese, L.,Lavecchia, A. (deposition date: 2014-03-18, release date: 2015-02-11) |
| Primary citation | Laghezza, A.,Montanari, R.,Lavecchia, A.,Piemontese, L.,Pochetti, G.,Iacobazzi, V.,Infantino, V.,Capelli, D.,De Bellis, M.,Liantonio, A.,Pierno, S.,Tortorella, P.,Conte Camerino, D.,Loiodice, F. On the Metabolically Active Form of Metaglidasen: Improved Synthesis and Investigation of Its Peculiar Activity on Peroxisome Proliferator-Activated Receptors and Skeletal Muscles. Chemmedchem, 2015 PubMed: 25641779 (PDB entries with the same primary citation) DOI: 10.1002/cmdc.201402462  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
