4PVD

Crystal structure of yeast methylglyoxal/isovaleraldehyde reductase Gre2 complexed with NADPH

Summary for 4PVD

Entry DOI	10.2210/pdb4pvd/pdb
Related	4PVC
Descriptor	NADPH-dependent methylglyoxal reductase GRE2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	rossmann fold, reductase, nadph binding, oxidoreductase
Biological source	Saccharomyces cerevisiae (yeast)
Cellular location	Cytoplasm : Q12068
Total number of polymer chains	4
Total formula weight	154372.58
Authors	Guo, P.C.,Bao, Z.Z.,Li, W.F.,Zhou, C.Z. (deposition date: 2014-03-17, release date: 2014-10-22, Last modification date: 2023-11-08)
Primary citation	Guo, P.C.,Bao, Z.Z.,Ma, X.X.,Xia, Q.,Li, W.F. Structural insights into the cofactor-assisted substrate recognition of yeast methylglyoxal/isovaleraldehyde reductase Gre2 Biochim.Biophys.Acta, 1844:1486-1492, 2014 Cited by PubMed: 24879127 DOI: 10.1016/j.bbapap.2014.05.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation