4PUN

tRNA-Guanine Transglycosylase (TGT) Apo-Structure pH 7.8

Summary for 4PUN

• Entry DOI: 10.2210/pdb4pun/pdb
• Related: 1PUD 4PUJ 4PUK 4PUL 4PUM 4PUN
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: transferase, guanine exchange enzyme, guanine, preq1, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43069.25

Authors

Neeb, M.,Heine, A.,Klebe, G. (deposition date: 2014-03-13, release date: 2014-07-16, Last modification date: 2023-09-20)

• Primary citation: Neeb, M.,Czodrowski, P.,Heine, A.,Barandun, L.J.,Hohn, C.,Diederich, F.,Klebe, G.; Chasing Protons: How Isothermal Titration Calorimetry, Mutagenesis, and pKa Calculations Trace the Locus of Charge in Ligand Binding to a tRNA-Binding Enzyme.; J.Med.Chem., 57:5554-5565, 2014; PubMed: 24955548; DOI: 10.1021/jm500401x

Experimental method

X-RAY DIFFRACTION (1.25 Å)