4PTJ

Ensemble model for Escherichia coli dihydrofolate reductase at 277K

Summary for 4PTJ

Entry DOI	10.2210/pdb4ptj/pdb
Related	4PST 4PSZ 4PTH
Descriptor	Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	rossmann fold, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	19346.02
Authors	Keedy, D.A.,van den Bedem, H.,Sivak, D.A.,Petsko, G.A.,Ringe, D.,Wilson, M.A.,Fraser, J.S. (deposition date: 2014-03-10, release date: 2014-05-14, Last modification date: 2023-09-20)
Primary citation	Keedy, D.A.,van den Bedem, H.,Sivak, D.A.,Petsko, G.A.,Ringe, D.,Wilson, M.A.,Fraser, J.S. Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR. Structure, 22:899-910, 2014 Cited by PubMed: 24882744 DOI: 10.1016/j.str.2014.04.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.05 Å)

Structure validation