4PSQ
Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with a non-retinoid ligand
Summary for 4PSQ
Entry DOI | 10.2210/pdb4psq/pdb |
Related | 3FMZ |
Descriptor | Retinol-binding protein 4, (1-benzyl-1H-imidazol-4-yl)[4-(2-chlorophenyl)piperazin-1-yl]methanone, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | retinol binding, disease mutation, secreted, sensory transduction, vision, vitamin a, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02753 |
Total number of polymer chains | 2 |
Total formula weight | 51434.00 |
Authors | |
Primary citation | Wang, Y.,Connors, R.,Fan, P.,Wang, X.,Wang, Z.,Liu, J.,Kayser, F.,Medina, J.C.,Johnstone, S.,Xu, H.,Thibault, S.,Walker, N.,Conn, M.,Zhang, Y.,Liu, Q.,Grillo, M.P.,Motani, A.,Coward, P.,Wang, Z. Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4. Bioorg.Med.Chem.Lett., 24:2885-2891, 2014 Cited by PubMed: 24835984DOI: 10.1016/j.bmcl.2014.04.089 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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