4PSQ

Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with a non-retinoid ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Retinol-binding protein 4	polymer	212	24620.5	2	UniProt (P02753) Pfam (PF00061) In PDB	Homo sapiens (human)	Plasma retinol-binding protein, PRBP, RBP
2	B, A	(1-benzyl-1H-imidazol-4-yl)[4-(2-chlorophenyl)piperazin-1-yl]methanone	non-polymer		380.9	2	Chemie (2WL)
3	B, A	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	B, A	1,2-ETHANEDIOL	non-polymer		62.1	20	Chemie (EDO)
5		water	water		18.0	142	Chemie (HOH)

Sequence modifications

B, A: 1 - 183 (UniProt: P02753)

PDB	External Database	Details
Met -28	-	EXPRESSION TAG
Ala -27	-	EXPRESSION TAG
Ser -26	-	EXPRESSION TAG
Met -25	-	EXPRESSION TAG
Ser -24	-	EXPRESSION TAG
Tyr -23	-	EXPRESSION TAG
Tyr -22	-	EXPRESSION TAG
His -21	-	EXPRESSION TAG
His -20	-	EXPRESSION TAG
His -19	-	EXPRESSION TAG
His -18	-	EXPRESSION TAG
His -17	-	EXPRESSION TAG
His -16	-	EXPRESSION TAG
Asp -15	-	EXPRESSION TAG
Tyr -14	-	EXPRESSION TAG
Asp -13	-	EXPRESSION TAG
Ile -12	-	EXPRESSION TAG
Pro -11	-	EXPRESSION TAG
Thr -10	-	EXPRESSION TAG
Thr -9	-	EXPRESSION TAG
Glu -8	-	EXPRESSION TAG
Asn -7	-	EXPRESSION TAG
Leu -6	-	EXPRESSION TAG
Tyr -5	-	EXPRESSION TAG
Phe -4	-	EXPRESSION TAG
Gln -3	-	EXPRESSION TAG
Gly -2	-	EXPRESSION TAG
Ala -1	-	EXPRESSION TAG
Met 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49241.0
Non-Polymers*	Number of molecules	24
	Total formula weight	2193.0
All*	Total formula weight	51434.0

*Water molecules are not included.