4PSQ

Crystal Structure of Retinol-Binding Protein 4 (RBP4) in complex with a non-retinoid ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Retinol-binding protein 4	polymer	212	24620.5	2	UniProt (P02753) Pfam (PF00061)	Homo sapiens (human)	Plasma retinol-binding protein, PRBP, RBP
2	C, M (B, A)	(1-benzyl-1H-imidazol-4-yl)[4-(2-chlorophenyl)piperazin-1-yl]methanone	non-polymer		380.9	2	Chemie (2WL)
3	D, N (B, A)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	E, F, G, H, I... (B, A)	1,2-ETHANEDIOL	non-polymer		62.1	20	Chemie (EDO)
5	AA, BA (B, A)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

B, A: 1 - 183 (UniProt: P02753)

PDB	External Database	Details
Met -28	-	expression tag
Ala -27	-	expression tag
Ser -26	-	expression tag
Met -25	-	expression tag
Ser -24	-	expression tag
Tyr -23	-	expression tag
Tyr -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Asp -15	-	expression tag
Tyr -14	-	expression tag
Asp -13	-	expression tag
Ile -12	-	expression tag
Pro -11	-	expression tag
Thr -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Ala -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49241.0
Non-Polymers*	Number of molecules	24
	Total formula weight	2193.0
All*	Total formula weight	51434.0

*Water molecules are not included.