4PRY
Caspase-8 specific unnatural amino acid peptides
Summary for 4PRY
Entry DOI | 10.2210/pdb4pry/pdb |
Related | 4JJ7 4JJ8 4JJE 4PRZ 4PS0 4PS1 |
Descriptor | Caspase-3, Ac-LETD-CHO (3 entities in total) |
Functional Keywords | protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42574 |
Total number of polymer chains | 2 |
Total formula weight | 33208.61 |
Authors | Wolan, D.W.,Gonzalez-Paez, G.E.,Vickers, C.J. (deposition date: 2014-03-06, release date: 2015-01-21, Last modification date: 2023-12-06) |
Primary citation | Vickers, C.J.,Gonzalez-Paez, G.E.,Litwin, K.M.,Umotoy, J.C.,Coutsias, E.A.,Wolan, D.W. Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids. Acs Chem.Biol., 9:2194-2198, 2014 Cited by PubMed: 25079698DOI: 10.1021/cb5004256 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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