4POP
ThiT with LMG139 bound
Summary for 4POP
Entry DOI | 10.2210/pdb4pop/pdb |
Related | 3RLB 4POV |
Descriptor | Thiamine transporter ThiT, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophene-2-carbaldehyde, ... (11 entities in total) |
Functional Keywords | s-component, thiamine-binding protein, ecf module, membrane, protein binding |
Biological source | Lactococcus lactis subsp. cremoris |
Cellular location | Cell membrane ; Multi-pass membrane protein : A2RI47 |
Total number of polymer chains | 2 |
Total formula weight | 50300.28 |
Authors | Swier, L.J.Y.M.,Guskov, A.,Slotboom, D.J. (deposition date: 2014-02-26, release date: 2014-09-17, Last modification date: 2024-02-28) |
Primary citation | Swier, L.J.,Monjas, L.,Guskov, A.,de Voogd, A.R.,Erkens, G.B.,Slotboom, D.J.,Hirsch, A.K. Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine. Chembiochem, 16:819-826, 2015 Cited by PubMed: 25676607DOI: 10.1002/cbic.201402673 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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