4PO7

Structure of the Sortilin:neurotensin complex at excess neurotensin concentration

4PO7 の概要

• エントリーDOI: 10.2210/pdb4po7/pdb
• 分子名称: Sortilin, Neurotensin/neuromedin N, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: 10 bladed beta-propeller, protein sorting receptor, neurotensin, glycosylation, trans golgi network, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 81715.12

構造登録者

Quistgaard, E.M.,Groftehauge, M.K.,Thirup, S.S. (登録日: 2014-02-25, 公開日: 2014-07-23, 最終更新日: 2020-10-21)

• 主引用文献: Quistgaard, E.M.,Grftehauge, M.K.,Madsen, P.,Pallesen, L.T.,Christensen, B.,Srensen, E.S.,Nissen, P.,Petersen, C.M.,Thirup, S.S.; Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin.; Protein Sci., 23:1291-1300, 2014; PubMed: 24985322; DOI: 10.1002/pro.2512

実験手法

X-RAY DIFFRACTION (2.66 Å)