4PMW

Structure of mouse Dis3L2 in complex with oligoU RNA substrate

Summary for 4PMW

• Entry DOI: 10.2210/pdb4pmw/pdb
• Descriptor: DIS3-like exonuclease 2, U-U-U-U-U-U-U-U-U-U-U-U-U-U, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: mirna regulation, exonuclease, rna complex, rna interference, hydrolase-rna complex, hydrolase/rna
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 4
• Total formula weight: 182772.87

Authors

Faehnle, C.R.,Walleshauser, J.,Joshua-Tor, L. (deposition date: 2014-05-22, release date: 2014-07-30, Last modification date: 2023-12-27)

• Primary citation: Faehnle, C.R.,Walleshauser, J.,Joshua-Tor, L.; Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.; Nature, 514:252-256, 2014; PubMed: 25119025; DOI: 10.1038/nature13553

Experimental method

X-RAY DIFFRACTION (2.95 Å)