4PLY

Crystal structure of ancestral apicomplexan malate dehydrogenase with malate.

Summary for 4PLY

• Entry DOI: 10.2210/pdb4ply/pdb
• Related: 4PLC 4PLF 4PLG 4PLH 4PLT 4PLV 4PLW 4PLZ
• Descriptor: malate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PYRUVIC ACID, ... (4 entities in total)
• Functional Keywords: ancestral sequence reconstruction, dehydrogenase, apicomplexa, specificity, oxidoreductase
• Biological source: Apicomplexa
• Total number of polymer chains: 8
• Total formula weight: 297523.59

Authors

Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L. (deposition date: 2014-05-19, release date: 2014-07-02, Last modification date: 2023-11-15)

• Primary citation: Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L.; An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.; Elife, 3:e02304-e02304, 2014; PubMed: 24966208; DOI: 10.7554/eLife.02304

Experimental method

X-RAY DIFFRACTION (1.9 Å)