4PLF
Crystal structure of ancestral apicomplexan lactate dehydrogenase with lactate.
Summary for 4PLF
Entry DOI | 10.2210/pdb4plf/pdb |
Related | 4PLC 4PLG 4PLH 4PLT 4PLV 4PLW 4PLY 4PLZ |
Descriptor | lactate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PYRUVIC ACID, ... (5 entities in total) |
Functional Keywords | ancestral sequence reconstruction, dehydrogenase, apicomplexa, specificity, oxidoreductase |
Biological source | Apicomplexa |
Total number of polymer chains | 2 |
Total formula weight | 74829.93 |
Authors | Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L. (deposition date: 2014-05-16, release date: 2014-07-02, Last modification date: 2023-11-15) |
Primary citation | Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L. An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3:e02304-e02304, 2014 Cited by PubMed: 24966208DOI: 10.7554/eLife.02304 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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