4PLC

Crystal structure of ancestral apicomplexan lactate dehydrogenase with malate.

Summary for 4PLC

Entry DOI	10.2210/pdb4plc/pdb
Related	4PLF 4PLG 4PLH 4PLT 4PLV 4PLW 4PLY 4PLZ
Descriptor	lactate dehydrogenase, PYRUVIC ACID, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	ancestral sequence reconstruction, dehydrogenase, apicomplexa, specificity, oxidoreductase
Biological source	Apicomplexa
Total number of polymer chains	4
Total formula weight	149659.86
Authors	Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L. (deposition date: 2014-05-16, release date: 2014-07-02, Last modification date: 2023-11-15)
Primary citation	Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L. An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3:e02304-e02304, 2014 Cited by PubMed: 24966208 DOI: 10.7554/eLife.02304 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation