4PK7

crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins

4PK7 の概要

• エントリーDOI: 10.2210/pdb4pk7/pdb
• 分子名称: Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total)
• 機能のキーワード: sister chromatid cohesion, cohesin subunits, protein-protein interaction, heat repeat, cell cycle
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 131948.27

構造登録者

Hara, K.,Chen, Z.,Tomchick, D.R.,Yu, H. (登録日: 2014-05-13, 公開日: 2014-09-03, 最終更新日: 2023-09-27)

• 主引用文献: Hara, K.,Zheng, G.,Qu, Q.,Liu, H.,Ouyang, Z.,Chen, Z.,Tomchick, D.R.,Yu, H.; Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.; Nat.Struct.Mol.Biol., 21:864-870, 2014; PubMed: 25173175; DOI: 10.1038/nsmb.2880

実験手法

X-RAY DIFFRACTION (2.95 Å)