4PK4

Myosin VI motor domain in the PPS state - from a Pi release state crystal, space group P212121 after long soaking with PO4

Summary for 4PK4

Entry DOI	10.2210/pdb4pk4/pdb
Related	4PFO
Descriptor	Unconventional myosin-VI, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	motor protein, motor domain, pre powerstroke state
Biological source	Sus scrofa (Pig)
Total number of polymer chains	1
Total formula weight	90393.66
Authors	Isabet, T.,Benisty, H.,Llinas, P.,Sweeney, H.L.,Houdusse, A. (deposition date: 2014-05-13, release date: 2015-04-29, Last modification date: 2023-12-20)
Primary citation	Llinas, P.,Isabet, T.,Song, L.,Ropars, V.,Zong, B.,Benisty, H.,Sirigu, S.,Morris, C.,Kikuti, C.,Safer, D.,Sweeney, H.L.,Houdusse, A. How actin initiates the motor activity of Myosin. Dev.Cell, 33:401-412, 2015 Cited by PubMed: 25936506 DOI: 10.1016/j.devcel.2015.03.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.78 Å)

Structure validation