4PIP

Engineered EgtD variant EgtD-M252V,E282A in complex with tryptophan and SAH

Summary for 4PIP

Entry DOI	10.2210/pdb4pip/pdb
Related	4PIM 4PIN 4PIO
Descriptor	Histidine-specific methyltransferase EgtD, TRYPTOPHAN, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total)
Functional Keywords	methyltransferase, ergothioneine, histidine betaine, transferase
Biological source	Mycobacterium smegmatis
Total number of polymer chains	4
Total formula weight	143208.98
Authors	Vit, A.,Seebeck, F.P.,Blankenfeldt, W. (deposition date: 2014-05-09, release date: 2014-12-03, Last modification date: 2023-09-27)
Primary citation	Vit, A.,Misson, L.,Blankenfeldt, W.,Seebeck, F.P. Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis. Chembiochem, 16:119-125, 2015 Cited by PubMed: 25404173 DOI: 10.1002/cbic.201402522 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation