4PHV

X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY

4PHV の概要

• エントリーDOI: 10.2210/pdb4phv/pdb
• 分子名称: HIV-1 PROTEASE, N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE (3 entities in total)
• 機能のキーワード: hydrolase(aspartic proteinase)
• 由来する生物種: Human immunodeficiency virus 1
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22899.08

構造登録者

Bone, R. (登録日: 1991-10-04, 公開日: 1993-10-31, 最終更新日: 2024-02-28)

• 主引用文献: Bone, R.,Vacca, J.P.,Anderson, P.S.,Holloway, M.K.; X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry; J.Am.Chem.Soc., 113:9382-, 1991

実験手法

X-RAY DIFFRACTION (2.1 Å)