4PE0
Crystal Structure of Calcium-loaded S100B bound to SBi4434
Summary for 4PE0
Entry DOI | 10.2210/pdb4pe0/pdb |
Related | 4PDZ 4PE1 4PE4 4PE7 |
Descriptor | Protein S100-B, 2-[(2-hydroxyethyl)sulfanyl]naphthalene-1,4-dione, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | malignant melanoma, calcium binding, covalent inhibitor, complex, metal binding protein-inhibitor complex, metal binding protein/inhibitor |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 2 |
Total formula weight | 21992.80 |
Authors | Cavalier, M.C.,Pierce, P.D.,Wilder, P.T.,Neau, D.,Toth, E.A.,Weber, D.J. (deposition date: 2014-04-22, release date: 2014-11-05, Last modification date: 2023-09-27) |
Primary citation | Cavalier, M.C.,Pierce, A.D.,Wilder, P.T.,Alasady, M.J.,Hartman, K.G.,Neau, D.B.,Foley, T.L.,Jadhav, A.,Maloney, D.J.,Simeonov, A.,Toth, E.A.,Weber, D.J. Covalent Small Molecule Inhibitors of Ca(2+)-Bound S100B. Biochemistry, 53:6628-6640, 2014 Cited by PubMed: 25268459DOI: 10.1021/bi5005552 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.08 Å) |
Structure validation
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