4PD4

Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action

Summary for 4PD4

Entry DOI	10.2210/pdb4pd4/pdb
Descriptor	Cytochrome b-c1 complex subunit 1, mitochondrial, Igh protein, Ig kappa chain V-V region HP 124E1, ... (18 entities in total)
Functional Keywords	cytochrome bc1 complex, membrane protein complex, antimalarial drug, inhibitor, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	11
Total formula weight	251150.07
Authors	Birth, D.,Kao, W.-C.,Hunte, C. (deposition date: 2014-04-17, release date: 2014-06-11, Last modification date: 2023-12-27)
Primary citation	Birth, D.,Kao, W.C.,Hunte, C. Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action. Nat Commun, 5:4029-4029, 2014 Cited by PubMed: 24893593 DOI: 10.1038/ncomms5029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.04 Å)

Structure validation