4P5M
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity
Summary for 4P5M
Entry DOI | 10.2210/pdb4p5m/pdb |
Related | 4P4K 4P4R 4P57 4P5K |
Descriptor | HLA class II histocompatibility antigen, DP alpha 1 chain, peptide,HLA class II histocompatibility antigen, DP beta 1 chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | cbd, autoimmunity, beryllium, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P20036 |
Total number of polymer chains | 8 |
Total formula weight | 186417.68 |
Authors | Wang, Y.,Dai, S.,Kappler, J. (deposition date: 2014-03-18, release date: 2014-08-27, Last modification date: 2023-12-27) |
Primary citation | Clayton, G.M.,Wang, Y.,Crawford, F.,Novikov, A.,Wimberly, B.T.,Kieft, J.S.,Falta, M.T.,Bowerman, N.A.,Marrack, P.,Fontenot, A.P.,Dai, S.,Kappler, J.W. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158:132-142, 2014 Cited by PubMed: 24995984DOI: 10.1016/j.cell.2014.04.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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