4P5K
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity
Summary for 4P5K
| Entry DOI | 10.2210/pdb4p5k/pdb |
| Related | 4P4K 4P4R 4P57 |
| Descriptor | HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, DP beta 1 chain (2 entities in total) |
| Functional Keywords | mhc, tcr, complex, hla, chronic beryllium disease, allergy, autoimmunity, immune system |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Cell membrane; Single-pass type I membrane protein: P20036 |
| Total number of polymer chains | 4 |
| Total formula weight | 91181.49 |
| Authors | Clayton, G.M.,Wang, Y.,Crawford, F.,Novikov, A.,Wimberly, B.T.,Kieft, J.S.,Falta, M.T.,Bowerman, N.A.,Marrack, P.,Fontenot, A.P.,Dai, S.,Kappler, J.W. (deposition date: 2014-03-17, release date: 2015-01-21, Last modification date: 2023-12-27) |
| Primary citation | Clayton, G.M.,Wang, Y.,Crawford, F.,Novikov, A.,Wimberly, B.T.,Kieft, J.S.,Falta, M.T.,Bowerman, N.A.,Marrack, P.,Fontenot, A.P.,Dai, S.,Kappler, J.W. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158:132-142, 2014 Cited by PubMed: 24995984DOI: 10.1016/j.cell.2014.04.048 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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