4P4Y
Hexamer formed by a macrocyclic peptide derived from beta-2-microglobulin (63-69) - (ORN)YLL(PHI)YTE(ORN)KVT(MAA)TVK
Summary for 4P4Y
Entry DOI | 10.2210/pdb4p4y/pdb |
Related | 4P4V 4P4W 4P4X 4P4Z |
Descriptor | CYCLIC HEXADECAPEPTIDE (ORN)YLL(PHI)YTE(ORN)KVT(MAA)TVK, SULFATE ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | hexamer, amyloid, beta-2-microglobulin, macrocycle, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 7 |
Total formula weight | 14753.35 |
Authors | Spencer, R.K.,Li, H.,Nowick, J.S. (deposition date: 2014-03-13, release date: 2015-05-06, Last modification date: 2023-12-27) |
Primary citation | Spencer, R.K.,Kreutzer, A.G.,Salveson, P.J.,Li, H.,Nowick, J.S. X-ray Crystallographic Structures of Oligomers of Peptides Derived from beta 2-Microglobulin. J.Am.Chem.Soc., 137:6304-6311, 2015 Cited by PubMed: 25915729DOI: 10.1021/jacs.5b01673 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.509 Å) |
Structure validation
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