4P4S

GMPPCP-bound stalkless-MxA

Summary for 4P4S

• Entry DOI: 10.2210/pdb4p4s/pdb
• Descriptor: Interferon-induced GTP-binding protein Mx1, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: gtpase, dynamin-related protein, antiviral, signaling protein, antiviral protein-hydrolase complex, antiviral protein/hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm . Isoform 2: Cytoplasm : P20591 P20591
• Total number of polymer chains: 2
• Total formula weight: 72230.92

Authors

Rennie, M.L.,McKelvie, S.A.,Bulloch, E.M.,Kingston, R.L. (deposition date: 2014-03-13, release date: 2014-10-22, Last modification date: 2023-09-27)

• Primary citation: Rennie, M.L.,McKelvie, S.A.,Bulloch, E.M.,Kingston, R.L.; Transient Dimerization of Human MxA Promotes GTP Hydrolysis, Resulting in a Mechanical Power Stroke.; Structure, 22:1433-1445, 2014; PubMed: 25295396; DOI: 10.1016/j.str.2014.08.015

Experimental method

X-RAY DIFFRACTION (3.3 Å)