4P4S
GMPPCP-bound stalkless-MxA
Summary for 4P4S
Entry DOI | 10.2210/pdb4p4s/pdb |
Descriptor | Interferon-induced GTP-binding protein Mx1, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | gtpase, dynamin-related protein, antiviral, signaling protein, antiviral protein-hydrolase complex, antiviral protein/hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm . Isoform 2: Cytoplasm : P20591 P20591 |
Total number of polymer chains | 2 |
Total formula weight | 72230.92 |
Authors | Rennie, M.L.,McKelvie, S.A.,Bulloch, E.M.,Kingston, R.L. (deposition date: 2014-03-13, release date: 2014-10-22, Last modification date: 2024-10-09) |
Primary citation | Rennie, M.L.,McKelvie, S.A.,Bulloch, E.M.,Kingston, R.L. Transient Dimerization of Human MxA Promotes GTP Hydrolysis, Resulting in a Mechanical Power Stroke. Structure, 22:1433-1445, 2014 Cited by PubMed: 25295396DOI: 10.1016/j.str.2014.08.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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