4P10
pro-carboxypeptidase U In Complex With 5-(3-aminopropyl)-1-propyl-6,7-dihydro-4H-benzimidazole-5-carboxylic acid
Summary for 4P10
| Entry DOI | 10.2210/pdb4p10/pdb |
| Descriptor | Carboxypeptidase B2, (5R)-5-(3-aminopropyl)-1-propyl-4,5,6,7-tetrahydro-1H-benzimidazole-5-carboxylic acid, ZINC ION, ... (6 entities in total) |
| Functional Keywords | inhibitor, drug discovery, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 47009.49 |
| Authors | Hallberg, K.,Sjogren, T. (deposition date: 2014-02-21, release date: 2014-08-13, Last modification date: 2023-12-20) |
| Primary citation | Brink, M.,Dahlen, A.,Olsson, T.,Polla, M.,Svensson, T. Design and synthesis of conformationally restricted inhibitors of active thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorg.Med.Chem., 22:2261-2268, 2014 Cited by PubMed: 24588961DOI: 10.1016/j.bmc.2014.02.010 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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