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4OYP

Human solAC Complexed with 1-Benzofuran-2-carboxylic acid

Summary for 4OYP
Entry DOI10.2210/pdb4oyp/pdb
Related4OYA 4OYB 4OYI 4OYM 4OYO 4OYW 4OYX 4OYZ 4OZ2 4OZ3
DescriptorAdenylate cyclase type 10, CHLORIDE ION, 1-benzofuran-2-carboxylic acid, ... (4 entities in total)
Functional Keywordslyase
Biological sourceHomo sapiens (Human)
Cellular locationCell membrane; Peripheral membrane protein; Cytoplasmic side: Q96PN6
Total number of polymer chains1
Total formula weight53664.43
Authors
Vinkovic, M. (deposition date: 2014-02-12, release date: 2014-04-02, Last modification date: 2023-12-27)
Primary citationSaalau-Bethell, S.M.,Berdini, V.,Cleasby, A.,Congreve, M.,Coyle, J.E.,Lock, V.,Murray, C.W.,O'Brien, M.A.,Rich, S.J.,Sambrook, T.,Vinkovic, M.,Yon, J.R.,Jhoti, H.
Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.
Chemmedchem, 9:823-832, 2014
Cited by
PubMed: 24616449
DOI: 10.1002/cmdc.201300480
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.28 Å)
Structure validation

217705

건을2024-03-27부터공개중

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