4OX2

I45T cytosolic phosphoenolpyruvate carboxykinase in complex with beta-sulfopyruvate and GTP

4OX2 の概要

• エントリーDOI: 10.2210/pdb4ox2/pdb
• 分子名称: Phosphoenolpyruvate carboxykinase, cytosolic [GTP], MANGANESE (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ... (8 entities in total)
• 機能のキーワード: kinase, gluconeogenesis, lyase
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 141300.11

構造登録者

Holyoak, T. (登録日: 2014-02-04, 公開日: 2014-06-11, 最終更新日: 2023-09-27)

• 主引用文献: Adams, D.R.,Yuan, H.,Holyoak, T.,Arajs, K.H.,Hakimi, P.,Markello, T.C.,Wolfe, L.A.,Vilboux, T.,Burton, B.K.,Fajardo, K.F.,Grahame, G.,Holloman, C.,Sincan, M.,Smith, A.C.,Wells, G.A.,Huang, Y.,Vega, H.,Snyder, J.P.,Golas, G.A.,Tifft, C.J.,Boerkoel, C.F.,Hanson, R.W.,Traynelis, S.F.,Kerr, D.S.,Gahl, W.A.; Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity.; Mol.Genet.Metab., 113:161-170, 2014; PubMed: 24863970; DOI: 10.1016/j.ymgme.2014.04.001

実験手法

X-RAY DIFFRACTION (2 Å)