4OWN

Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 5-fluoroanthranilate, PRPP and Magnesium

Summary for 4OWN

Entry DOI	10.2210/pdb4own/pdb
Related	4OWM 4OWO 4OWQ 4OWS 4OWU 4OWV
Descriptor	Anthranilate phosphoribosyltransferase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... (8 entities in total)
Functional Keywords	anthranilic acids, magnesium, tryptophan, inhibitor, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	79488.07
Authors	Castell, A.,Cookson, T.V.M.,Short, F.L.,Lott, J.S. (deposition date: 2014-02-02, release date: 2014-04-23, Last modification date: 2023-12-27)
Primary citation	Cookson, T.V.,Castell, A.,Bulloch, E.M.,Evans, G.L.,Short, F.L.,Baker, E.N.,Lott, J.S.,Parker, E.J. Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461:87-98, 2014 Cited by PubMed: 24712732 DOI: 10.1042/BJ20140209 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.11 Å)

Structure validation