4OWN
Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 5-fluoroanthranilate, PRPP and Magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Anthranilate phosphoribosyltransferase | polymer | 378 | 38848.9 | 2 | UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5) | Mycobacterium tuberculosis | |
| 2 | C, D, J, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | E (A) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 4 | F, G, M, N (A, B) | 2-amino-5-fluorobenzoic acid | non-polymer | 155.1 | 4 | Chemie (5RG) | |||
| 5 | H, I, O, P (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | L (B) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 1 | Chemie (PRP) | |||
| 7 | Q, R (B) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 8 | S, T (A, B) | water | water | 18.0 | 404 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 370 (UniProt: P66992)
| PDB | External Database | Details |
|---|---|---|
| Leu 371 | - | expression tag |
| Glu 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77697.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1790.3 | |
| All* | Total formula weight | 79488.1 |
