4OWN

Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 5-fluoroanthranilate, PRPP and Magnesium

4OWN の概要

• エントリーDOI: 10.2210/pdb4own/pdb
• 関連するPDBエントリー: 4OWM 4OWO 4OWQ 4OWS 4OWU 4OWV
• 分子名称: Anthranilate phosphoribosyltransferase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... (8 entities in total)
• 機能のキーワード: anthranilic acids, magnesium, tryptophan, inhibitor, transferase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79488.07

構造登録者

Castell, A.,Cookson, T.V.M.,Short, F.L.,Lott, J.S. (登録日: 2014-02-02, 公開日: 2014-04-23, 最終更新日: 2023-12-27)

• 主引用文献: Cookson, T.V.,Castell, A.,Bulloch, E.M.,Evans, G.L.,Short, F.L.,Baker, E.N.,Lott, J.S.,Parker, E.J.; Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.; Biochem.J., 461:87-98, 2014; PubMed: 24712732; DOI: 10.1042/BJ20140209

実験手法

X-RAY DIFFRACTION (2.11 Å)