4OUC
Structure of human haspin in complex with histone H3 substrate
Summary for 4OUC
Entry DOI | 10.2210/pdb4ouc/pdb |
Descriptor | Serine/threonine-protein kinase haspin, Histone H3.2, SODIUM ION, ... (7 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, transferase, histone, kinase substrate complex, chromatin regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q8TF76 Q71DI3 |
Total number of polymer chains | 2 |
Total formula weight | 43040.55 |
Authors | Chaikuad, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2014-02-15, release date: 2014-04-16, Last modification date: 2023-09-20) |
Primary citation | Maiolica, A.,de Medina-Redondo, M.,Schoof, E.M.,Chaikuad, A.,Villa, F.,Gatti, M.,Jeganathan, S.,Lou, H.J.,Novy, K.,Hauri, S.,Toprak, U.H.,Herzog, F.,Meraldi, P.,Penengo, L.,Turk, B.E.,Knapp, S.,Linding, R.,Aebersold, R. Modulation of the chromatin phosphoproteome by the haspin protein kinase. Mol Cell Proteomics, 13:1724-1740, 2014 Cited by PubMed: 24732914DOI: 10.1074/mcp.M113.034819 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report