4OUC

Structure of human haspin in complex with histone H3 substrate

4OUC の概要

• エントリーDOI: 10.2210/pdb4ouc/pdb
• 分子名称: Serine/threonine-protein kinase haspin, Histone H3.2, SODIUM ION, ... (7 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, transferase, histone, kinase substrate complex, chromatin regulator
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: Q8TF76 Q71DI3
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43040.55

構造登録者

Chaikuad, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2014-02-15, 公開日: 2014-04-16, 最終更新日: 2023-09-20)

• 主引用文献: Maiolica, A.,de Medina-Redondo, M.,Schoof, E.M.,Chaikuad, A.,Villa, F.,Gatti, M.,Jeganathan, S.,Lou, H.J.,Novy, K.,Hauri, S.,Toprak, U.H.,Herzog, F.,Meraldi, P.,Penengo, L.,Turk, B.E.,Knapp, S.,Linding, R.,Aebersold, R.; Modulation of the chromatin phosphoproteome by the haspin protein kinase.; Mol Cell Proteomics, 13:1724-1740, 2014; PubMed: 24732914; DOI: 10.1074/mcp.M113.034819

実験手法

X-RAY DIFFRACTION (1.9 Å)