4OTP
Crystal structure of the catalytic domain of the human RioK1 atypical protein kinase in complex with ADP/Mg2+
Summary for 4OTP
Entry DOI | 10.2210/pdb4otp/pdb |
Descriptor | Serine/threonine-protein kinase RIO1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | atypical kinase domain, rio domain, ribosome biogenesis, pre-40s, preribosome, phosphorylation, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 42276.73 |
Authors | LaRonde, N.A.,Kiburu, I.N. (deposition date: 2014-02-14, release date: 2014-07-02, Last modification date: 2014-08-13) |
Primary citation | Ferreira-Cerca, S.,Kiburu, I.,Thomson, E.,LaRonde, N.,Hurt, E. Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes. Nucleic Acids Res., 42:8635-8647, 2014 Cited by PubMed: 24948609DOI: 10.1093/nar/gku542 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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