4OTP

Crystal structure of the catalytic domain of the human RioK1 atypical protein kinase in complex with ADP/Mg2+

4OTP の概要

• エントリーDOI: 10.2210/pdb4otp/pdb
• 分子名称: Serine/threonine-protein kinase RIO1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: atypical kinase domain, rio domain, ribosome biogenesis, pre-40s, preribosome, phosphorylation, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42276.73

構造登録者

LaRonde, N.A.,Kiburu, I.N. (登録日: 2014-02-14, 公開日: 2014-07-02, 最終更新日: 2014-08-13)

• 主引用文献: Ferreira-Cerca, S.,Kiburu, I.,Thomson, E.,LaRonde, N.,Hurt, E.; Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes.; Nucleic Acids Res., 42:8635-8647, 2014; PubMed: 24948609; DOI: 10.1093/nar/gku542

実験手法

X-RAY DIFFRACTION (2.7 Å)