4ORK

Crystal Structure of the Phosphotransferase Domain of the Bifunctional Aminoglycoside Resistance Enzyme AAC(6')-Ie-APH(2'')-Ia

Summary for 4ORK

• Entry DOI: 10.2210/pdb4ork/pdb
• Descriptor: Bifunctional AAC/APH, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: kinase, antibiotic resistance, aminoglycosides and gtp, transferase
• Biological source: Staphylococcus aureus
• Cellular location: Cytoplasm: P0A0C1
• Total number of polymer chains: 4
• Total formula weight: 145760.04

Authors

Smith, C.A.,Toth, M.,Bhattacharya, M.,Frase, H.,Vakulenko, S.B. (deposition date: 2014-02-11, release date: 2014-07-02, Last modification date: 2024-02-28)

• Primary citation: Smith, C.A.,Toth, M.,Bhattacharya, M.,Frase, H.,Vakulenko, S.B.; Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia.; Acta Crystallogr.,Sect.D, 70:1561-1571, 2014; PubMed: 24914967; DOI: 10.1107/S1399004714005331

Experimental method

X-RAY DIFFRACTION (2.3 Å)