4OO7
THE 1.55A CRYSTAL STRUCTURE of NAF1 (MINER1): THE REDOX-ACTIVE 2FE-2S PROTEIN
Summary for 4OO7
Entry DOI | 10.2210/pdb4oo7/pdb |
Related | 3FNV 4OOA |
Descriptor | CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER (3 entities in total) |
Functional Keywords | membrane bound, thiazolidinedione, oxidative stress, metal binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Single-pass membrane protein: Q8N5K1 |
Total number of polymer chains | 2 |
Total formula weight | 15735.33 |
Authors | Tamir, S.,Eisenberg-Domovich, Y.,Colman, A.R.,Stofleth, J.T.,Lipper, C.H.,Paddock, M.L.,Jenning, P.A.,Livnah, O.,Nechushtai, R. (deposition date: 2014-01-31, release date: 2014-07-02, Last modification date: 2024-02-28) |
Primary citation | Tamir, S.,Eisenberg-Domovich, Y.,Conlan, A.R.,Stofleth, J.T.,Lipper, C.H.,Paddock, M.L.,Mittler, R.,Jennings, P.A.,Livnah, O.,Nechushtai, R. A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties. Acta Crystallogr.,Sect.D, 70:1572-1578, 2014 Cited by PubMed: 24914968DOI: 10.1107/S1399004714005458 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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