4OO2
Streptomyces globisporus C-1027 FAD dependent (S)-3-chloro-β-tyrosine-S-SgcC2 C-5 hydroxylase SgcC apo form
Summary for 4OO2
Entry DOI | 10.2210/pdb4oo2/pdb |
Related | 4HX6 4R82 |
Descriptor | Chlorophenol-4-monooxygenase, CALCIUM ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | structural genomics, enzyme discovery for natural product biosynthesis, natpro, putative hpab-family monooxygenase, fad binding, oxidoreductase, psi-biology |
Biological source | Streptomyces globisporus |
Total number of polymer chains | 4 |
Total formula weight | 235716.58 |
Authors | Cao, H.,Xu, W.,Bingman, C.A.,Lohman, J.R.,Yennamalli, R.,Shen, B.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2014-01-29, release date: 2014-02-12, Last modification date: 2023-03-22) |
Primary citation | Chang, C.Y.,Lohman, J.R.,Cao, H.,Tan, K.,Rudolf, J.D.,Ma, M.,Xu, W.,Bingman, C.A.,Yennamalli, R.M.,Bigelow, L.,Babnigg, G.,Yan, X.,Joachimiak, A.,Phillips, G.N.,Shen, B. Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55:5142-5154, 2016 Cited by PubMed: 27560143DOI: 10.1021/acs.biochem.6b00713 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.63 Å) |
Structure validation
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