4ONL

Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P

Summary for 4ONL

• Entry DOI: 10.2210/pdb4onl/pdb
• Related: 4ONM 4ONN
• Descriptor: Ubiquitin-conjugating enzyme E2 variant 2, Ubiquitin-conjugating enzyme E2 N (3 entities in total)
• Functional Keywords: ubc13, mms2, e2, ubiquitin conjugating enzyme, ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P61088
• Total number of polymer chains: 2
• Total formula weight: 35048.19

Authors

Hodge, C.D.,Edwards, R.A.,Glover, J.N.M. (deposition date: 2014-01-28, release date: 2015-05-06, Last modification date: 2024-02-28)

• Primary citation: Hodge, C.D.,Edwards, R.A.,Markin, C.J.,McDonald, D.,Pulvino, M.,Huen, M.S.,Zhao, J.,Spyracopoulos, L.,Hendzel, M.J.,Glover, J.N.; Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.; Acs Chem.Biol., 10:1718-1728, 2015; PubMed: 25909880; DOI: 10.1021/acschembio.5b00222

Experimental method

X-RAY DIFFRACTION (1.35 Å)