4OND

Ancestral Steroid Receptor 2 DBD helix mutant - ERE DNA complex

Summary for 4OND

• Entry DOI: 10.2210/pdb4ond/pdb
• Related: 4OLN 4OOR
• Descriptor: Ancestral SR2 Helix Mutant, 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*G)-3', ... (5 entities in total)
• Functional Keywords: nuclear receptor dna binding domain, zinc finger, transcription factor, coregulators, transcription-dna complex, transcription/dna
• Biological source: synthetic construct
• Total number of polymer chains: 8
• Total formula weight: 58744.63

Authors

Ortlund, E.O.,Murphy, M.N. (deposition date: 2014-01-28, release date: 2014-10-29, Last modification date: 2024-02-28)

• Primary citation: McKeown, A.N.,Bridgham, J.T.,Anderson, D.W.,Murphy, M.N.,Ortlund, E.A.,Thornton, J.W.; Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.; Cell(Cambridge,Mass.), 159:58-68, 2014; PubMed: 25259920; DOI: 10.1016/j.cell.2014.09.003

Experimental method

X-RAY DIFFRACTION (2.253 Å)