4OME
X-ray structure of human glutamate carboxypeptidase II in complex with DCCBL, a urea based inhibitor with distal carborane moiety
Summary for 4OME
Entry DOI | 10.2210/pdb4ome/pdb |
Descriptor | Glutamate carboxypeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | hydrolase, metallopeptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane ; Single-pass type II membrane protein . Isoform PSMA': Cytoplasm: Q04609 |
Total number of polymer chains | 1 |
Total formula weight | 83158.28 |
Authors | Barinka, C.,Ptacek, J.,Novakova, Z.,Byun, Y. (deposition date: 2014-01-27, release date: 2015-02-18, Last modification date: 2020-07-29) |
Primary citation | Barinka, C.,Ptacek, J.,Novakova, Z.,Byun, Y. X-ray structure of human glutamate carboxypeptidase II in complex with DCCBL, a urea based inhibitor with distal carborane moiety To be Published, |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
Download full validation report