4OKE

Structure of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo

Summary for 4OKE

Entry DOI	10.2210/pdb4oke/pdb
Related	4OKJ 4OKK
Descriptor	3'-5' exoribonuclease Rv2179c/MT2234.1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	m. tuberculosis, ribonuclease, capsular polysaccharides, virulence, hydrolase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	40166.87
Authors	Berisio, R.,Romano, M. (deposition date: 2014-01-22, release date: 2014-05-21, Last modification date: 2024-03-20)
Primary citation	Romano, M.,van de Weerd, R.,Brouwer, F.C.C.,Roviello, G.N.,Lacroix, R.,Sparrius, M.,van den Brink-van Stempvoort, G.,Maaskant, J.J.,van der Sar, A.M.,Appelmelk, B.J.,Geurtsen, J.J.,Berisio, R. Structure and Function of RNase AS, a Polyadenylate-Specific Exoribonuclease Affecting Mycobacterial Virulence In Vivo Structure, 22:719-730, 2014 Cited by PubMed: 24704253 DOI: 10.1016/j.str.2014.01.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation