4OJN

Crystal structure of human muscle L-lactate dehydrogenase

Summary for 4OJN

• Entry DOI: 10.2210/pdb4ojn/pdb
• Related: 4OKN
• Descriptor: L-lactate dehydrogenase A chain, PENTAETHYLENE GLYCOL, GLYCEROL, ... (4 entities in total)
• Functional Keywords: rossmann fold, nadh/nad+ cofactor, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00338
• Total number of polymer chains: 8
• Total formula weight: 301641.26

Authors

Kolappan, S.,Craig, L. (deposition date: 2014-01-21, release date: 2014-12-03, Last modification date: 2024-02-28)

• Primary citation: Kolappan, S.,Shen, D.L.,Mosi, R.,Sun, J.,McEachern, E.J.,Vocadlo, D.J.,Craig, L.; Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.; Acta Crystallogr.,Sect.D, 71:185-195, 2015; PubMed: 25664730; DOI: 10.1107/S1399004714024791

Experimental method

X-RAY DIFFRACTION (2.4 Å)