4OJK

Structure of the cGMP Dependent Protein Kinase II and Rab11b Complex

4OJK の概要

• エントリーDOI: 10.2210/pdb4ojk/pdb
• 関連するPDBエントリー: 1ZXA 2F9L 2F9M 3NMD
• 分子名称: Ras-related protein Rab-11B, cGMP-dependent protein kinase 2, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: small gtpase, leucine zipper, trafficking, serine/threonine kinase, membrane associated, hydrolase-protein binding complex, hydrolase/protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side : Q15907; Apical cell membrane ; Lipid-anchor : Q64595
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56410.66

構造登録者

Reger, A.S.,Yang, M.P.,Guo, E.,Kim, C. (登録日: 2014-01-21, 公開日: 2014-08-06, 最終更新日: 2023-09-20)

• 主引用文献: Reger, A.S.,Yang, M.P.,Koide-Yoshida, S.,Guo, E.,Mehta, S.,Yuasa, K.,Liu, A.,Casteel, D.E.,Kim, C.; Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions.; J.Biol.Chem., 289:25393-25403, 2014; PubMed: 25070890; DOI: 10.1074/jbc.M114.575894

実験手法

X-RAY DIFFRACTION (2.657 Å)