4OII
West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab
Summary for 4OII
Entry DOI | 10.2210/pdb4oii/pdb |
Related | 4OIE 4OIG |
Descriptor | NON-STRUCTURAL PROTEIN NS1, Light Chain of Fab fragment of 22NS1 Antibody, Heavy Chain of Fab fragment of 22NS1 Antibody, ... (4 entities in total) |
Functional Keywords | west nile virus, antibody, fab, neutralizing, flavivirus, non-structural protein, ns1, viral protein-immune system complex, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein/immune system |
Biological source | West Nile virus (WNV) More |
Cellular location | Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Lumenal side . Host nucleus . Secreted . Virion membrane ; Multi-pass membrane protein : U3N977 |
Total number of polymer chains | 6 |
Total formula weight | 135472.64 |
Authors | Edeling, M.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-01-19, release date: 2014-03-05, Last modification date: 2017-11-22) |
Primary citation | Edeling, M.A.,Diamond, M.S.,Fremont, D.H. Structural basis of Flavivirus NS1 assembly and antibody recognition. Proc.Natl.Acad.Sci.USA, 111:4285-4290, 2014 Cited by PubMed: 24594604DOI: 10.1073/pnas.1322036111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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