Summary for 4OI8
Entry DOI | 10.2210/pdb4oi8/pdb |
Related | 4OI7 |
Descriptor | Advanced glycosylation end product-specific receptor, 5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3', 5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3', ... (4 entities in total) |
Functional Keywords | ig fold, dna binding, transport protein, signaling protein-dna complex, signaling protein/dna |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: Q15109 |
Total number of polymer chains | 4 |
Total formula weight | 62471.29 |
Authors | |
Primary citation | Sirois, C.M.,Jin, T.,Miller, A.L.,Bertheloot, D.,Nakamura, H.,Horvath, G.L.,Mian, A.,Jiang, J.,Schrum, J.,Bossaller, L.,Pelka, K.,Garbi, N.,Brewah, Y.,Tian, J.,Chang, C.,Chowdhury, P.S.,Sims, G.P.,Kolbeck, R.,Coyle, A.J.,Humbles, A.A.,Xiao, T.S.,Latz, E. RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA. J.Exp.Med., 210:2447-2463, 2013 Cited by PubMed: 24081950DOI: 10.1084/jem.20120201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.101 Å) |
Structure validation
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