4OFR

Crystal structure of AR-LBD bound with co-regulator peptide

4OFR の概要

• エントリーDOI: 10.2210/pdb4ofr/pdb
• 関連するPDBエントリー: 4OEA 4OED 4OEY 4OEZ 4OFU 4OGH 4OH5 4OH6 4OHA 4OIL 4OIU 4OJ9 4OJB 4OK1 4OKB 4OKT 4OKW 4OKX 4OLM
• 分子名称: Androgen receptor, co-regulator peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total)
• 機能のキーワード: alpha-helix, hormone/growth factor receptor, phosphorylation, hormone receptor-peptide complex, hormone receptor/peptide
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P10275
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30799.98

構造登録者

Liu, J.S.,Hsu, C.L.,Wu, W.G. (登録日: 2014-01-15, 公開日: 2014-08-20, 最終更新日: 2023-09-20)

• 主引用文献: Hsu, C.L.,Liu, J.S.,Wu, P.L.,Guan, H.H.,Chen, Y.L.,Lin, A.C.,Ting, H.J.,Pang, S.T.,Yeh, S.D.,Ma, W.L.,Chen, C.J.,Wu, W.G.,Chang, C.; Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.; Mol Oncol, 8:1575-1587, 2014; PubMed: 25091737; DOI: 10.1016/j.molonc.2014.06.009

実験手法

X-RAY DIFFRACTION (2.26 Å)