4OEM
Crystal structure of Cathepsin C in complex with dipeptide substrates
Summary for 4OEM
Entry DOI | 10.2210/pdb4oem/pdb |
Related | 4OEL |
Descriptor | Dipeptidyl peptidase 1 Heavy chain, Dipeptidyl peptidase 1 Light chain, GLYCINE, ... (9 entities in total) |
Functional Keywords | beta barrel, dipeptidyl aminopeptidase i, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 51015.61 |
Authors | Zhao, B.,Smallwood, A.,Concha, N. (deposition date: 2014-01-13, release date: 2015-03-25, Last modification date: 2020-07-29) |
Primary citation | Rubach, J.K.,Cui, G.,Schneck, J.L.,Taylor, A.N.,Zhao, B.,Smallwood, A.,Nevins, N.,Wisnoski, D.,Thrall, S.H.,Meek, T.D. The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis. Biochemistry, 51:7551-7568, 2012 Cited by PubMed: 22928782DOI: 10.1021/bi300719b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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